Early toxicosis commonly emerges during the initial trimester of pregnancy, usually manifesting between the second and approximately the 12-15 week of gestation. This condition often presents with symptoms such as excessive salivation, fatigue, nausea, and frequent vomiting in pregnant women, all of which reflect disruptions in both the central and autonomic nervous systems. Recognized as a multifactorial disorder, early toxicosis represents a complex constellation of gestational complications. Among its diverse etiological factors, chorionic gonadotropin is considered a primary driver influencing the maternal physiological response. In more severe and resistant forms, women may develop pronounced electrolyte imbalances and metabolic alkalosis. Although there are no universally accepted guidelines for assessing the severity of gestosis, clinicians rely on a combination of laboratory findings and clinical assessment, with emphasis on markers related to cardiovascular, hepatic, and renal function. The current research focuses on identifying specific biochemical blood parameters that can serve as reliable indicators for determining the intensity of early toxicosis during pregnancy.
