TY  - JOUR
T1  - Histopathological Trends of Orofacial Squamous Cell Carcinoma in a Tanzanian Cohort of 465 Patients
A1  - Karpal Singh Sohal
A1  - Sira Stanslaus Owibingire
A1  - Jeremiah Robert Moshy
A1  - David K Deoglas
A1  - Paulo J Laizer
A1  - Boniphace M Kalyanyama
A1  - Erick Sylivester
JF  - Archive of International Journal of Cancer and Allied Science
JO  - Arch Int J Cancer Allied Sci
SN  - 3108-4834
Y1  - 2022
VL  - 2
IS  - 1
DO  - 10.51847/AEHrcMQ1kn
SP  - 29
EP  - 36
N2  - Orofacial squamous cell carcinoma (OfSCC) represents a significant proportion of malignant head and neck lesions, with an estimated incidence of up to 90%. This study investigated the histopathological traits of OfSCC in Tanzanian patients, focusing on factors such as patient age, gender, and tumor location. The study analyzed cases diagnosed between 2016 and 2021 at the Oral and Maxillofacial Surgery Department, Muhimbili National Hospital. The data collected included patient demographics, tumor sites, and histological grading. The results showed an average patient age of 55.85 years, with a slightly higher incidence in males (male-to-female ratio 1.4:1). The majority of patients were in the age group of 60 years and above, accounting for 45.2% of cases. Intraoral tumors were the most common (87.6%), with the tongue and gingiva/alveolar ridge being the most affected sites (34.5% and 25.6%, respectively). For extra-oral cases, the midfacial region was the most frequently involved (68.5%). Histological analysis showed that 72% of the cases were classified as grade I. The findings indicated a predominance of older male patients, with the tongue, gingiva, and buccal mucosa being the primary intraoral sites and the midface the predominant extra-oral location.
UR  - https://smerpub.com/article/histopathological-trends-of-orofacial-squamous-cell-carcinoma-in-a-tanzanian-cohort-of-465-patients-cpxigl4rybagguj
ER  -