TY  - JOUR
T1  - Minimal Deviation Adenocarcinoma of the Uterine Cervix: Diagnostic Challenges and Recent Insights
A1  - Cristina Secosan
A1  - Oana Balint
A1  - Aurora Ilian
A1  - Lavinia Balan
A1  - Ligia Balulescu
A1  - Andrei Motoc
A1  - Delia Zahoi
A1  - Dorin Grigoras
A1  - Laurentiu Pirtea
JF  - Archive of International Journal of Cancer and Allied Science
JO  - Arch Int J Cancer Allied Sci
SN  - 3108-4834
Y1  - 2021
VL  - 1
IS  - 1
DO  - 10.51847/PQXMl7sBaR
SP  - 39
EP  - 46
N2  - Minimal deviation adenocarcinoma (MDA) of the cervix is a highly differentiated form of adenocarcinoma that presents a significant diagnostic challenge. Due to its subtle microscopic features, MDA is often mistaken for benign conditions, which confuses pathologists and complicates its diagnosis in gynecological oncology. This leads to frequent misinterpretation and some cases are mistakenly diagnosed as benign, leading to inappropriate management. Both false-positive and false-negative MDA diagnoses are common in cervical biopsies and can have serious consequences for patient treatment. Immunohistochemistry plays an important role in the accurate diagnosis of MDA. This review summarizes the key clinical and pathological features, reviews benign mimics, and explores the immunohistochemical and molecular markers that assist in the correct diagnosis of MDA.
UR  - https://smerpub.com/article/minimal-deviation-adenocarcinoma-of-the-uterine-cervix-diagnostic-challenges-and-recent-insights-ojuejt1yhwqfhuk
ER  -