%0 Journal Article %T Navigating Ethical Challenges in COVID-19 Vaccination Programs: A Qualitative Study of Health Worker Perspectives %A Roya Malekzadeh %A Ghasem Abedi %A Arash Ziapour %A Murat Yıldırım %A Afshin Amirkhanlou %J Asian Journal of Ethics in Health and Medicine %@ 3108-5059 %D 2025 %V 5 %N 1 %R 10.51847/bLhOjE57Ew %P 299-311 %X Following the emergence of the COVID-19 pandemic, numerous nations focused on developing and delivering reliable vaccines to manage the outbreak and safeguard community well-being. The deployment of immunization efforts has raised several moral challenges that require careful identification and resolution. For this reason, the current investigation aimed to explore the ethical aspects of COVID-19 immunization as viewed by frontline healthcare personnel. This qualitative investigation took place in 2022 across northern Iran. It involved 23 healthcare professionals with at least 5 years of practical experience and who actively participated in COVID-19 immunization initiatives. Information gathering began with organized, semi-structured discussions, continued through snowball sampling, and ended when no new insights emerged. The process then included converting the discussions into written form, pinpointing key meaning segments, assigning codes, organizing codes by shared characteristics and alignment, deriving overarching themes, and evaluating those themes with content analysis methods.  Reviewing the accounts shared by participants yielded five core theme categories and fifteen supporting sub-categories concerning the ethical dimensions of COVID-19 immunization. The primary categories encompassed secure, regulated vaccine manufacturing; vaccine distribution; equity; honoring personal choice; and responsibility. The sub-categories covered adherence to established scientific and moral guidelines, vaccine performance and cost-benefit balance, lack of serious negative reactions, distribution of supplies for vaccine provision, vaccine accessibility, variety and completeness of substitute vaccine options, vaccine distribution sequencing, emphasis on at-risk groups within the population, individual patient independence (equal entitlements), collective societal independence, independence of healthcare deliverers, accurate disclosure of facts, disclosure of vaccine reactions, and societal confidence along with uptake. Leaders within the healthcare framework need adequate readiness to address the moral issues arising from COVID-19 immunization programs. It is thus suggested to avoid rushed immunization implementation, increase focus on immunization safety benchmarks, ensure ample supplies for full-scale vaccine availability, carefully weigh group benefits against personal preferences, and meet the expectations of the broader population.  %U https://smerpub.com/article/navigating-ethical-challenges-in-covid-19-vaccination-programs-a-qualitative-study-of-health-worker-gac3q0eb0eqikrk