This study aimed to assess the familiarity of pharmacy students and Arab pharmacists with e-learning as a means of transferring pharmaceutical information. It focused on their social media and internet usage, as well as the frequency of utilizing Web 2.0 tools in their everyday routines. The cross-sectional study surveyed 680 participants, predominantly aged 18-30 years, with a majority being females who had internet access. Most of the respondents (n = 491 (72.2%)) reported intermediate internet and computer skills, with most using the Internet for educational activities (n = 609 (89.6%)). Nearly all participants (n = 635 (93.4%)) accessed the internet every day, and over half (n = 360 (53.0%)) spent more than 2 hours daily using Web 2.0 tools and social media. However, more than half of the participants were unfamiliar with e-learning (n = 367 (54.0%)), and the majority had never participated in an online course (n = 484 (71.2%)). Despite this, nearly all participants expressed either high or intermediate confidence in e-learning (n = 669 (98.4%)), and the large majority felt confident in using Web 2.0 tools to aid interactive learning (n = 548 (80.6%) and n = 524 (77%), respectively). The findings of this study indicate strong potential for integrating web 2.0 tools and e-learning into pharmacy education.
