Written by Rosa Coppola
Published in Vol 1 Issue 1, 2021
Advancements in targeted therapy have significantly influenced modern cancer treatment. Among these, epidermal growth factor receptor (EGFR) inhibitors are widely utilized for managing metastatic, recurrent, and advanced malignancies. This report discusses a 74-year-old male diagnosed with metastatic colorectal cancer who experienced symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) alongside an acneiform eruption during cetuximab therapy in combination with FOLFOX chemothe
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Written by Gaye Keser
Published in Vol 1 Issue 1, 2021
This study aimed to assess the level of oral cancer awareness among medical professionals in Turkey. This study included 90 medical doctors who were provided with a 25-item questionnaire. These questions assessed their knowledge of oral cancer risk factors, screening methods, attitudes toward oral cancer, management of oral care, and general cancer awareness of the disease. All respondents identified cigarette use and viral infections as risk factors, with 95.6% also confirming alcohol consumpti
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Written by Harishankar Mahto
Published in Vol 1 Issue 1, 2021
Chronic inflammation is a key factor in the development of colorectal cancer (CRC). Lymphotoxin-alpha (LT-α), a multifunctional pro-inflammatory cytokine, has shown both tumor-promoting and tumor-suppressing properties. The relationship between the intronic LT-α +252A/G single-nucleotide polymorphism (SNP) and various cancers, including CRC, has been widely studied with inconsistent findings. This study investigated the association between the LT-α +252A/G SNP and CRC susceptibility in the Kashm
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Written by Jay Hoover
Published in Vol 1 Issue 1, 2021
In recent years, the consumption of vitamin and mineral supplements (VMS) has increased in various patient groups, especially among people with cancer. This study aims to assess and compare the awareness and attitudes toward VMS among healthy individuals and cancer patients. A structured questionnaire was distributed to both cancer patients and a healthy control group collecting information about their sociodemographic profiles, knowledge, and perspectives regarding VMS use. Among the 778 respon
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Written by Cristina Secosan
Published in Vol 1 Issue 1, 2021
Minimal deviation adenocarcinoma (MDA) of the cervix is a highly differentiated form of adenocarcinoma that presents a significant diagnostic challenge. Due to its subtle microscopic features, MDA is often mistaken for benign conditions, which confuses pathologists and complicates its diagnosis in gynecological oncology. This leads to frequent misinterpretation and some cases are mistakenly diagnosed as benign, leading to inappropriate management. Both false-positive and false-negative MDA diagn
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Written by Vanessa M. LópezOzuna
Published in Vol 1 Issue 1, 2021
Water-pipe smoking (WPS), a common form of tobacco use, is particularly prevalent among young women in the Middle East. The smoke produced by WPS contains harmful substances similar to those found in cigarettes and is often associated with an increased risk of various cancers, including breast cancer. However, the specific genes affected by WPS and the mechanisms driving cancer initiation and progression, particularly in breast cancer, remain largely unknown. This study investigated the effects
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