Prostate cancer significantly affects the quality of life, with psychological factors such as anxiety, depression, and stress further worsening this effect. This study aimed to investigate the relationship between quality of life and mental health conditions—namely anxiety, depression, and stress—in people with prostate cancer. A descriptive-analytical design was used, involving 100 prostate cancer patients who were selected through convenience sampling. Participants completed a quality-of-life questionnaire along with the Hospital Anxiety and Depression Scale (HADS). Data were analyzed using SPSS version 21 software. The mean scores for quality of life, stress, anxiety, and depression were 50.70, 12.87, 14.60, and 12.52, respectively. A negative and significant correlation was found between quality of life and stress (-0.583), depression (-0.329), and anxiety (-0.312). These results indicate that mental health factors such as anxiety and depression significantly reduce the quality of life of prostate cancer patients. The findings emphasize the importance of incorporating psychological support in the treatment plan to improve the quality of life in these patients.
