Written by Parin Salim Sidat
Published in Vol 2 Issue 1, 2022
Aromatic heterocyclic compounds with five- and six-membered rings containing heteroatoms such as sulfur (S), oxygen (O), and nitrogen (N) have been widely studied due to their promising pharmacological potential. These compounds are essential for life, and the heteroatoms in the ring structures enhance interactions with amino acids, improving properties such as lipophilicity, solubility, and absorption. These attributes play a key role in reducing transactivation, which in turn boosts the therap
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Written by Orhan Kayira
Published in Vol 2 Issue 1, 2022
Breast cancer is a major global health concern and ranks as one of the leading causes of cancer-related mortality in women. This research focuses on utilizing the stochastic gradient boosting (SGB) technique to classify breast cancer data from open-access sources and identify key risk factors. The dataset was employed to develop a classification model, with SGB used for the disease classification process. The performance of the model was assessed using metrics such as accuracy, balanced accuracy
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Written by Vlad Denis Constantin
Published in Vol 2 Issue 1, 2022
This review focuses on colorectal cancer (CRC), which ranks as the third most common cancer and the fourth leading cause of cancer-related mortality worldwide. Despite its prevalence in older adults, only 1% to 4% of cases are reported among individuals aged 25 to 30 years. Risk factors for CRC include a family history of colorectal cancer, dietary habits, alcohol use, smoking, and inflammatory bowel disease. A thorough literature search was conducted across databases such as Medline, PubMed, Em
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Written by Karpal Singh Sohal
Published in Vol 2 Issue 1, 2022
Orofacial squamous cell carcinoma (OfSCC) represents a significant proportion of malignant head and neck lesions, with an estimated incidence of up to 90%. This study investigated the histopathological traits of OfSCC in Tanzanian patients, focusing on factors such as patient age, gender, and tumor location. The study analyzed cases diagnosed between 2016 and 2021 at the Oral and Maxillofacial Surgery Department, Muhimbili National Hospital. The data collected included patient demographics, tumo
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Written by Damian Mojsak
Published in Vol 2 Issue 1, 2022
Ewing’s sarcoma, a rare and highly aggressive tumor, is prone to recurrence even after extensive surgery and often metastasizes early. Typically seen in children and adolescents aged 10–20 years, it affects older individuals in approximately 30% of cases. This report details a 58-year-old man presenting with a foot tumor, back pain, and left leg discomfort. A chest x-ray revealing a lung mass led to a referral to the Pulmonology Department, but the diagnosis was delayed for months, worsening the
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Written by Deep Shankar Pruthi
Published in Vol 2 Issue 1, 2022
Cancer is generally associated with aging, with the risk of developing most cancer types rising significantly in midlife and continuing to increase with age. However, adolescents and young adults represent a unique demographic where cancers typically seen in older adults are increasingly being diagnosed. Tumors in this age group exhibit distinct characteristics when compared to those found in younger children or older adults, and management of these patients presents unique challenges due to the
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