Obesity is a multifaceted chronic disease that poses a significant health risk due to its association with cardiovascular and metabolic disorders. Among the various factors contributing to obesity, adipokines—hormones secreted by adipose tissue—such as leptin, adiponectin, and visfatin play a key role in regulating metabolic processes. This study investigated the effect of chronic emotional stress on the secretion of these adipokines in the blood serum of obese rats. The analysis showed that stress-induced decreases in leptin levels may lead to eating disorders, whereas visfatin levels are influenced by factors beyond adipose tissue mass. The findings suggest that chronic stress, combined with obesity, may accelerate the onset of insulin resistance, and further complicate metabolic health.
