Written by Naoki Todayama
Published in Vol 3 Issue 2, 2023
Carcinoma developing at the colostomy site following an abdominoperineal resection (APR) is an extremely rare event, with only a small number of instances documented in the available literature. In the absence of biopsy confirmation, such growths can often be mistaken for conditions such as hyperplasia or granulation tissue, especially at the stoma edges, complicating the diagnosis. We describe a unique case of a man in his late 50s who underwent an abdominoperineal resection due to rectal cance
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Written by Namita Singh
Published in Vol 3 Issue 2, 2023
The Ki-67 labelling index (LI) is an important marker used to assess cell proliferation in glioma diagnosis, providing valuable insights into tumor growth and potentially contributing to prognosis. This study investigates Ki-67 expression in astrocytic tumors and its association with clinicopathological features. We documented the clinical and radiological details of 43 glioma patients. Histopathological grade and morphology were assessed by H&E slide examination, while the Ki-67 labelling index
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Written by Jorge Guillen
Published in Vol 3 Issue 2, 2023
The global incidence and mortality rates of cancer are rapidly escalating, with prostate cancer ranking as the second most prevalent form of cancer in men, affecting approximately 1.41 million people worldwide (according to data from the World Health Organization (WHO)). Stevioside, a naturally occurring compound, has shown promising results in inhibiting the growth of cancer cells. This research seeks to investigate the molecular pathways responsible for the chemopreventive anticancer effects o
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Written by Karim Mashhour
Published in Vol 3 Issue 2, 2023
This study was conducted with the primary objective of evaluating and contrasting the acute toxicity outcomes associated with two radiotherapy modalities—3D-CRT and SIB-IMRT—administered in the preoperative setting for patients diagnosed with locally advanced rectal cancer (LARC). A total of 40 individuals who met the diagnostic criteria for LARC were enrolled and randomly allocated into two equal cohorts. Group A underwent 3D-CRT in combination with concurrent capecitabine, while group B receiv
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Written by Ngoc Dung Nguyen
Published in Vol 3 Issue 2, 2023
Recent evidence suggests that the PRIMA prognostic index (PRIMA-PI) may serve as a straightforward tool for risk stratification in patients with follicular lymphoma (FL). This study aimed to provide further insight into the prognosis of FL and retrospectively evaluated the prognostic utility of PRIMA-PI in comparison with the follicular lymphoma international prognostic index 2 (FLIPI2). A total of 45 newly diagnosed FL patients who received chemotherapy were included in this analysis. All patie
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Written by Soobia Saeed
Published in Vol 3 Issue 2, 2023
Although neural tissue cancers are frequently regarded as terminal, the precise origins and molecular or cellular mechanisms underlying these conditions remain elusive. Despite existing knowledge, the progression patterns and secondary effects associated with different brain tumors have not yet been fully mapped out. Cerebrospinal fluid (CSF) leakage remains a prevalent diagnostic indicator in tumor detection, and in this context, enzymes associated with brain cancer were analyzed. The primary o
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Written by Arina Romanovna Maslyakova
Published in Vol 3 Issue 2, 2023
The use of selenium nanoparticles in pharmaceutical research is well-documented in the scientific literature, particularly regarding their therapeutic potential in treating a variety of conditions such as hepatitis C, cancer, thyroid disorders, cardiovascular diseases, asthma, and more. This research investigated the effect of selenium nanoparticles on cancer tumor development. The study involved five groups of white laboratory mice: group 1, a healthy control group, group 2, a negative control
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