Written by Amal Ahmed Mohamed
Published in Vol 2 Issue 2, 2022
Type 2 diabetes mellitus (T2DM) is a significant global health challenge. Recent studies have shown that biomarkers such as microRNAs, especially miRNAs, are altered during the progression of T2DM and its associated complications, reflecting the mechanisms of the disease. This study focused on analyzing the expression of miRNA-224 in Egyptian T2DM patients and investigating its association with diabetic complications. A total of 205 participants were enrolled in this case-control study, of which
Read More
Written by Malik Adewoyin
Published in Vol 2 Issue 2, 2022
The comparative study of complementary species has become a promising strategy for advancing our understanding of disease models. Zebrafish and medaka stand as two of the leading fish models in biomedical research, with their increased prominence over the past three decades. Although zebrafish is more widely studied than medaka, both species offer complementary advantages. Despite their similarities, there are subtle anatomical and transcriptomic differences between the two. The completion of ge
Read More
Written by O. Lazoura
Published in Vol 2 Issue 2, 2022
Multidetector computed tomography (MDCT) has emerged as a promising non-invasive imaging technique for assessing vascular anatomy and characterizing atherosclerotic plaque morphology across various arterial regions. MDCT allows for comprehensive assessment of the entire arterial system and enables visualization of the vessel wall, including quantification of both calcified and non-calcified plaques. This study aimed to evaluate the morphological characterization of atherosclerotic plaques in cor
Read More
Written by Banyameen Iqbal
Published in Vol 2 Issue 2, 2022
Erdheim-Chester disease (ECD) is an uncommon, multisystem disorder categorized as non-Langerhans cell histiocytosis, with its cause still unknown. It mostly affects middle-aged individuals, with a slight male predominance. Radiologically, the disease is characterized by symmetric sclerotic lesions in the long bones, while histopathologically, foamy histiocytes are found in various affected areas. The diagnosis is confirmed by immunohistochemistry (IHC) with CD68. This case report presents a 60-y
Read More
Written by Soobia Saeed
Published in Vol 2 Issue 2, 2022
Cancers that affect neural tissue, particularly brain tumors, are often associated with poor prognoses. However, the precise cellular and molecular mechanisms behind their progression and associated complications remain incompletely understood. While considerable knowledge exists regarding different types of brain tumors, the processes by which they disseminate and inflict damage on adjacent brain regions are still unclear. This study examines the hypothesis that leakage of cerebrospinal fluid (
Read More
Written by Fathimath Ina Shareef
Published in Vol 2 Issue 2, 2022
The present study aimed to investigate the transmission, clinical features, and advances in countermeasures and treatment of monkeypox. Monkeypox is a DNA virus in the Poxviridae family, specifically classified under the Orthopoxvirus genus. Historically confined to central and western Africa, monkeypox made global headlines in 2022 due to widespread outbreaks in regions where it was previously rare, including North America, Europe, Asia, and Australasia. On 23 July 2022, the World Health Organi
Read More
