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Journal of Medical Sciences and Interdisciplinary Research

Volume 1, Issue 1 (2021)

Acute Kidney Injury in COVID-19 Patients: A Meta-Review of Systematic Studies
Written by Fabrizio Fabrizi   Published in Vol 1 Issue 1, 2021
The global impact of the COVID-19 pandemic has been widespread, and acute kidney injury (AKI) is a significant risk among individuals infected with SARS-CoV-2. This systematic review combines the findings of several systematic reviews on the incidence of AKI in COVID-19 patients. The review adhered to the PRISMA guidelines and conducted an extensive search of databases, including OVID, the Cochrane Library, EMBASE, ProQuest, PubMed, ScienceDirect, Scopus, and Web of Science until March 17, 2021.
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Characteristics of Various Training Methods in the “Pharmacy” Specialty
Written by Mariia Sergeevna Soboleva   Published in Vol 1 Issue 1, 2021
The available data on previous distant learning models and interactive methods in the field of “Pharmacy,” detailing their features, pros, and cons, are limited. This study aims to examine the components of different educational methods used at the Far Eastern State Medical University. A survey was conducted among 267 students enrolled in the “Pharmacy” program at the Faculty of Pharmacy and Biomedicine (higher education) and the Medico-Pharmaceutical College (secondary education). Key advantage
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Molecular Insights into Proprotein Convertase Subtilisin/Kexin Type 9 Mutations in Vietnamese Hypercholesterolemia Cases
Written by Phuong Dong Tran Nguyen   Published in Vol 1 Issue 1, 2021
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a crucial enzyme involved in the regulation of circulating low-density lipoprotein cholesterol (LDL-C). Variations in the PCSK9 gene can have significant effects on LDL receptor degradation—gain-of-function mutations accelerate receptor breakdown and contribute to familial hypercholesterolemia (FH), while loss-of-function mutations increase receptor availability, lower LDL-C levels, and reduce the risk of coronary heart disease. The geneti
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A Clinical Case Report on Eczema Treatment through Liver Heat Clearance and Detoxification
Written by Tao Zeng   Published in Vol 1 Issue 1, 2021
Eczema, a common non-communicable skin disorder, has been a long-standing concern. Current treatment protocols primarily focus on the skin itself, often relying on corticosteroids and other palliative drugs that can lead to significant side effects. Traditional Chinese Medicine (TCM) offers an alternative approach by addressing the underlying liver-skin axis. This case report describes the successful treatment of an 11-year-old girl with chronic eczema using TCM, specifically through liver clear
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Development of a New Keto Acid Precursor for Lambda-Carrageenan Oxidation via Alkaline Permanganate
Written by Refat M. Hassan   Published in Vol 1 Issue 1, 2021
The present study aimed at developing a new keto acid precursor for the oxidation of lambda-carrageenan via alkaline permanganate. A new class of keto-acid derivatives of lambda-carrageenan (LCAR), in the form of sulfated polysaccharides, was synthesized by oxidizing LCAR with permanganate ions in an alkaline environment at pH levels greater than 12. The reactants MnO4-, LCAR, and NaF were combined in precise stoichiometric ratios in alkaline solutions with pH values above 12. The mixture was st
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Exploring the Diagnosis and Therapeutic Approaches for Vitreous Hemorrhage
Written by Filippo Confalonieri   Published in Vol 1 Issue 1, 2021
Retinal vessels are vulnerable to damage from a variety of factors, including retinal tears, retinal detachment, sickle cell disease, macular degeneration, aneurysms, trauma, and venous occlusion, which can lead to retinal bleeding, commonly referred to as vitreous hemorrhage. This review highlights the advances made in the treatment of vitreous hemorrhage. This review was based on articles selected from the PubMed database, using the following key terms: diagnosis, vitreous hemorrhage, risk fac
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Thrombotic Impact on Muscle Tissue: Histological Insights in Gastrointestinal Cancer Cases
Written by Petro Bodnar   Published in Vol 1 Issue 1, 2021
A frequent complication observed in cancer patients is thrombosis, which affects both arterial and venous circulation. However, the exact mechanisms of blood clot formation and the development of disseminated intravascular coagulation (DIC) remain unclear. This study performed a morpho-histological examination of the lower limb muscles in two groups of cancer patients who also experienced deep vein thrombosis leading to thrombus migration. In both groups, which succumbed to pulmonary embolism fo
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