Written by Suyeon Kim
Published in Vol 4 Issue 2, 2024
Dedifferentiated liposarcoma (DDL), exhibiting divergent heterologous differentiation, is a rare entity with a variable reported incidence. These tumors typically arise in the retroperitoneum, often attaining substantial size and presenting at advanced stages, thereby posing significant diagnostic and therapeutic challenges. We report a rare case of recurrent DDL with dual heterologous differentiation—osteosarcomatous and chondrosarcomatous—in an elderly male initially presenting with symptoms m
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Written by Lesheng Huang
Published in Vol 4 Issue 2, 2024
Port-site metastasis after laparoscopic cholecystectomy in patients with gallbladder adenocarcinoma is an uncommon but serious concern in oncology. This disease is often challenging because of its delayed onset and the subsequent impact on prognosis. In this case, a 42-year-old woman developed a metastasis at the epigastric port site, 6 years following her laparoscopic cholecystectomy for gallbladder adenocarcinoma. The metastasis appeared as an ulcerative mass with features of squamous differen
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Written by Nirmal Ghati
Published in Vol 4 Issue 2, 2024
Due to the widespread nature of breast cancer and its significant impact on the quality of life for those affected, this study aimed to evaluate how palliative care education affects the quality of life of women with breast cancer. In this clinical trial, 46 breast cancer patients were randomly assigned to either an intervention group or a control group. While the control group received standard care, the intervention group participated in 4 weeks of specialized palliative care training. The Mis
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Written by Maria Lopez-Ramos
Published in Vol 4 Issue 2, 2024
Angiogenesis is a key factor in cancer progression, which is influenced by the expression of VEGFR-1, VEGFR-2, and VEGFR-3. Several therapeutic agents, including axitinib, regorafenib, cediranib, and sorafenib, are commonly used in treating cancer, although they can cause side effects such as thrombocytopenia and leukopenia. The current study sought to evaluate how bicyclo derivatives (1-27) interact with VEGFR-1, VEGFR-2, and VEGFR-3, using the 3hng, 2oh4, and 4sbj proteins, along with axitinib
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Written by Mohammed Sayed Mohammed
Published in Vol 4 Issue 2, 2024
Oral cancer, a malignant growth originating in the tissues of the oral cavity, ranks as the eighth most common cancer globally. Its high mortality rate is largely attributed to diagnoses occurring at advanced stages. Although histological examination remains the gold standard of diagnostic, it necessitates invasive tissue sampling. In contrast, liquid biopsy has recently gained attention as a non-invasive and promising alternative for the diagnosis of oral cancer. This method analyzes tumor-deri
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Written by Saeed Albalawi
Published in Vol 4 Issue 2, 2024
Access to accurate data concerning gynecological malignancies plays a critical role in effective health planning and policymaking. To date, no study has specifically examined the burden of gynecological cancer within the region of Tabuk, Saudi Arabia. This study sought to address that gap by evaluating its prevalence. A retrospective analysis was conducted at King Fahd Specialists Hospital, one of the four randomly selected main healthcare institutions in Tabuk City, Kingdom of Saudi Arabia. The
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Written by Meryem El Ouazzani
Published in Vol 4 Issue 2, 2024
Merkel cell carcinoma (MCC) is an aggressive form of skin cancer that usually occurs in older individuals, often with a history of prolonged sun exposure. This rare malignancy has been associated with various factors, including ultraviolet light, compromised immune function, and the presence of the Merkel cell polyomavirus (MCPyV). Despite ongoing discussions regarding the origin of the cancer cells, this tumor exhibits characteristics similar to the Merkel cells normally found in the skin, both
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