Written by Elisabetta Rosellini
Published in Vol 4 Issue 1, 2024
Thrombosis of vascular prostheses is one of the most important complications following surgical procedures on the lower extremity arteries. Unfortunately, preventing the surgical thread from interacting with flowing blood is nearly impossible, which makes the surgical site prone to thrombosis. This study aimed to investigate the potential for increasing the thromboresistance of polypropylene suture material by modifying its surface with heparin through chemical inoculation. To achieve this goal,
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Written by Milena Kostadinova
Published in Vol 4 Issue 1, 2024
Regenerative medicine offers innovative solutions through cell therapy and tissue engineering techniques to address irreparable bone damage. Engineered structures play an important role in enhancing the body’s natural healing process, especially in cases where extensive bone loss prevents natural recovery. This article provides an overview of the most commonly used scaffolds in tissue engineering for bone regeneration. Given that bone is a rigid and inflexible tissue, scaffolds designed for bone
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Written by Yalan Zhou
Published in Vol 4 Issue 1, 2024
Alzheimer’s disease (AD) is a complex neurodegenerative disorder that affects millions worldwide. This review aims to investigate the role of pharmacogenomics in the treatment of AD. Pharmacogenomic strategies aim to improve the efficacy and safety of treatments by identifying genetic factors that influence drug metabolism. These approaches include genetic testing to identify individuals at higher risk for AD and discovering new drug targets based on the genetic causes of the disease. For exampl
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Written by Oscar Solmell
Published in Vol 4 Issue 1, 2024
Chronic low back pain (cLBP) typically presents as pain radiating from the back into the dermatome of the affected nerve root. Magnetic resonance imaging (MRI) is the preferred diagnostic tool for evaluating the spine in patients with cLBP. The objective of this study is to investigate the relationship between pain, disability, and disc herniation, focusing on patients with severe disc prolapse (grade 3). The research included 70 participants, with pain intensity measured for both back and leg d
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Written by Aichetou Bouh
Published in Vol 4 Issue 1, 2024
Cancer treatments can significantly affect a patient’s nutritional health, with chemotherapy causing changes in weight and body composition that can influence treatment outcomes. This study aims to examine the changes in weight and body composition during the first cycle of neoadjuvant chemotherapy and explore how these changes relate to factors such as gender, age, body fat percentage, tumor location, and time since diagnosis. This study involved 139 patients undergoing cancer treatment, with a
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Written by Markha Suleymanovna Umarova
Published in Vol 4 Issue 1, 2024
The detrimental effect of vibration, which is considered one of the main physical factors in production, requires comprehensive scientific exploration. This study investigates how whole-body vibration influences protein metabolism using laboratory animals as a model. Two series of experiments were conducted involving a total of 30 white rats housed under uniform environmental conditions. Animals in group 1 were subjected to vibration exposure, whereas group 2 served as the control and did not ex
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Written by Felix OghenemaroEnwa
Published in Vol 4 Issue 1, 2024
This study investigates the prevalence of parasitic infections among people residing in rural communities and focuses on identifying the predominant parasites, associated risk factors, and potential preventive measures. A cross-sectional survey was conducted on 50 participants aged 12 to 56 years, selected based on defined inclusion criteria from Abraka and surrounding rural areas in Delta State, Nigeria. Stool specimens were collected and promptly analyzed in the departmental laboratory using s
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Written by Mateusz Piotr Krukowski
Published in Vol 4 Issue 1, 2024
Adverse Childhood Experiences (ACEs) are linked to numerous detrimental effects on physical, mental, and behavioral well-being. Nevertheless, no definitive threshold for ACE scores in relation to health consequences has been firmly established. This lack of clarity has resulted in the application of varying thresholds to classify elevated scores. The objective of this investigation is to determine a threshold at which ACEs demonstrate a notable connection to adverse long-term health conditions.
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Written by Khalid Mustafa Darwish
Published in Vol 4 Issue 1, 2024
During the COVID-19 pandemic, Infection Prevention and Control (IPC) played a critical role in minimizing viral transmission within healthcare settings. This study investigated factors that either hindered or promoted IPC adherence among healthcare workers (HCWs) during the COVID-19 crisis in Kampala City, Uganda. Fourteen key informants from 12 health facilities in Nakawa Division participated, including three government-run and nine private not-for-profit facilities. Participants were either d
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Written by Stefano Alberto Rinaldi
Published in Vol 4 Issue 1, 2024
Limited information exists on the clinical courses of COVID-19 cases in low-resource nations, such as Rwanda. Therefore, the objectives of this investigation were to evaluate 1) the clinical results for individuals hospitalized due to COVID-19 in Rwanda, and 2) the effectiveness of the Universal Vital Assessment (UVA) scoring system in forecasting death among these cases, in contrast to the sequential organ failure assessment (SOFA) and quick SOFA (qSOFA) systems. A retrospective analysis was pe
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Written by Michael Andreas Engel
Published in Vol 4 Issue 1, 2024
Insufficient levels of essential micronutrients negatively impact the well-being of females in their childbearing years, affect fetal development during gestation, and influence the physical and cognitive progress of children in nations across sub-Saharan Africa. This research sought to assess nutrient consumption patterns in females who are neither pregnant nor breastfeeding, living in seven administrative areas within Tanzania's Mbeya area, through the application of a single-day food reca
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Written by Andreas Soren Kristensen
Published in Vol 4 Issue 1, 2024
Plants of the Achillea genus have traditionally been employed to manage digestive disorders. This study aimed to investigate the mechanisms underlying the effects of the decocted extract of Achillea odorata L. (ADE), particularly its influence on neurotransmitters regulating gastrointestinal motility, as well as its impact on intestinal transit (IT) and gastric emptying (GE). Mice were administered ADE at doses of 100, 200, or 400 mg·kg⁻¹, followed one hour later by a phenol red meal. In a separ
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Written by Sofia Valentina Moreno
Published in Vol 4 Issue 1, 2024
Whole-body vibration (WBV) represents an innovative training approach that enhances muscular power, range of motion, and postural control in older adults. The practicality and effectiveness of thermotherapy sessions lasting 20–30 minutes—achieved by wrapping a 73 °C heat source in several towel layers to reduce skin contact temperature to 40–43 °C—are increasingly supported by practical uses and research evidence. Research indicates that such thermal applications improve the extensibility of ten
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